scott@vtx-cpd.com
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Replying to Raquel M. 24/03/2022 - 16:32
Hey.
This is a slightly tricky one. I would definitely never use omeprazole in this prophylactic way and I would not start omeprazole so that NSAIDs could be started again.
However, as always, if a NSAID causes an ulcer, then omeprazole is totally appropriate and the NSAID discontinued.
I think in this case it is not clear that there was an ulcer. I would definitely not stop start the NSAID with omeprazole in-between.
Could you consider an alternative in this case for the OA pain:
https://www2.zoetis.co.uk/products-solutions/dogs/oa-pain/librela
Have you used a lot of Librela?
I am sorry that is not a very definitive answer, it is a tricky one.
Scott π
Replying to Raquel M. 24/03/2022 - 16:32
Hello.
I hope you are well. I have popped the first part of your question below so I do not miss anything:
”A colleague had discontinued NSAIDs in a dog on long term nsaid use for arthritis throughout his elbows and hips. He had discontinued it because after questioning the owner had reported that the dog had been eating grass for the last few months. The dog had been doing really well on multimodal pain management along with the NSAIDs. I wasnβt aware that eating grass was a clinical sign of nausea or indication of GI ulceration from NSAID use. Are you able to shed some light on this? Is this something I should questioning owners about or is this something unproven?”
Eating grass can indeed be a clinical sign of nausea, but it is really non specific. They can obviously eat grass for lots of other reasons. Again, you could see this with ulceration from NSAIDs secondary to nausea. It is a fine line to walk as you would obviously not want to continue NSAIDs in a dog that was developing ulcers. I would have considered a couple of days of anti-emetic therapy first and see what kind of response there was. Abdominal ultrasound may also be useful for ulceration, although small ulcers are difficult to detect. You could possibly consider faecal occult blood testing as another way of looking for ulceration/bleeding.
Overall, this is not something I would routinely be asking owners about but could flag up the possibility of nausea.
Scott π
Replying to Katerina N. 10/03/2022 - 11:42
Hello Katerina!
I hope you are safe and well and enjoying the course.
Sound like a brilliant approach to me!
Scott π
Replying to Nathalie Cunha 09/03/2022 - 12:32
No guilt needed!
I spent 10 years of my career advising the approach. The hope is that with the acute cases, things get back to normal quite quickly. I agree with Hilary that the GI diets are the way to go, but each case is individual and if you are really challenged with what the pet and owners will do, then a little bit of home cooked short term will be fine.
Scott π
Replying to Nathalie Cunha 09/03/2022 - 12:27
Haha!
FeLV and FIV were negative!
Scott π
Replying to scott@vtx-cpd.com 05/04/2022 - 12:31
Hey.
Thoracic radiography was unremarkable!
Abdominal ultrasound
Lymph Nodes: A single peri-gastric lymph node is large and hypoechoic. All other lymph nodes are normal.
Stomach: The gastric wall at the level of the body and pyloric antrum is diffusely, severely thickened with loss of the normal wall layer architecture.
No other abnormalities were noted in the abdomen
Next steps?
Scott π
Replying to austeja Zykute 13/03/2022 - 15:57
Thanks Austeja.
I hope you are well. I would definitely be considering some sort of hypereosinophilic syndrome… cats love to do things with eosinophils!
I think ultrasound and radiography sound great! I will pop the results of these tests below! Would love to hear your comments.
Scott π
Replying to Nathalie Cunha 09/03/2022 - 12:27
Hello Nathalie.
Thank you for your response! Differentials for the eosinophilia would include:
Gastrointestinal disease β eosinophilic inflammatory bowel disease, gastrointestinal eosinophilic sclerosing fibroplasia
Parasitism β gastrointestinal helminths, ectoparasites
Asthma
Allergic dermatitis
Eosinophilic granuloma complex
Hypereosinophilic syndrome
Neoplastic β paraneoplastic e.g. lymphoma, mast cell tumour, squamous cell carcinoma, thymoma
Fungal infections e.g cryptococcus
HypoadrenocorticismI would indeed consider faecal analysis. The other option would be to repeat a course of parasitic treatment. Normally a 7 day course of fenbendazole!
Scott π
Replying to Rosie Webster 04/04/2022 - 18:07
Welcome!
I hope you are well. I hope you also like the less ECC parts of the course too! You never know… you might see a hypothyroid case OOH!?
Scott π
Replying to Hillary N. 04/04/2022 - 12:25
Really helpful.
Thank you.
Scott π
Replying to Julie S. 23/03/2022 - 14:51
Hello Julie.
I am so sorry for the delay in getting back to you. No idea how I missed this! I hope you have had a lovely weekend and you are enjoying the course.
One of the natural products that has some evidence regarding nausea in people is ginger. I could find one paper (quite old) that used it in dogs for chemotherapy induced nausea:
https://pubmed.ncbi.nlm.nih.gov/9254112/
There does seem to be quite a bit of evidence in the human literature:
https://pubmed.ncbi.nlm.nih.gov/23638927/
Ginger is not something I have experience of giving as a stand alone supplement. The other option for GI cases would be to use a probiotic. Less evidence for vomiting, nausea, reflux, but not likely to do any harm.
I know some veterinary diets will contain ginger, which might be interesting to discuss more.
I would be interested to hear the experience of others?
Hope that helps.
Scott π
Replying to Emma Holt 01/04/2022 - 14:21
Hello again.
I am going to look in to the Fortifolra a bit more and speak to Silke too. I would agree with that approach regarding probiotic then diet. I would also be comfortable trying Vivomixx more in cats. Danielle was concerned about the palatability issue compared to Fortiflora.
Scott π
I have had the following back from Danielle:
”Hi Scott,
Good Qs.
As far as I know, still no NP wet β unless Steph can correct me.
I would usually try a pro-biotic or symbiotic course before a hydrolysed diet trial for this reason. I donβt know about VSL#3 instead β but I know a lady who will knowβ¦
Dxx”
I will speak to Silke at Edinburgh regarding the Forti flora too.
Scott π
This is a brilliant question!
The main evidence for Fortiflora is regarding Tritrichomonas foetus. So my recommendation is extrapolated a bit from this.
I have forwarded your question to Danielle Gunn Moore and Stephanie Lalor! Feline goddesses! I want to make sure I give you the correct answer… I will let you know what they say!
Scott π
Replying to Natalie H. 01/04/2022 - 12:23
Hello Natalie.
I hope you are safe and well.
Regarding diet with chronic enteropathy. Generally if there is no response after 2 weeks I would recommend trying a different diet. Generally if there is going to be a positive response you will see this quite quickly. The longer diet trials are more appropriate for dermatological conditions.
Hope that helps. Have a lovely weekend!
Scott π
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