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scott@vtx-cpd.com

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Viewing 15 posts - 676 through 690 (of 2,377 total)
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  • scott@vtx-cpd.com
    Keymaster

    Replying to Janette B. 24/06/2024 - 08:59

    Hi Janette,

    Great to see you again! Thanks for continuing to work with us. Your expertise in Anaesthesia and Analgesia is incredibly valuable, and I’m looking forward to your whirlwind tour. There’s indeed so much to learn and discuss.

    Best regards,

    Scott 🙂

    scott@vtx-cpd.com
    Keymaster

    Replying to Matteo R. 27/06/2024 - 12:12

    Hi Matteo,

    Great to see you here! Your work in small animal surgery, particularly with open-heart surgery for mitral valve repair and congenital heart conditions, sounds incredibly cool. I’m looking forward to your lecture and the tips and tricks you have to offer.

    Best regards,

    Scott 🙂

    scott@vtx-cpd.com
    Keymaster

    Replying to Inge B. 24/06/2024 - 20:45

    Hi Inge,

    Congratulations on your recent exam success and becoming a VTS (Oncology)! That’s an amazing achievement. I’m looking forward to your insights on the chemotherapy journey and any tips you can share for managing chronic illness patients.

    Thank you for being here, and I look forward to learning from you and discussing the different types of cancers we’re treating.

    Best regards,

    Scott 🙂

    scott@vtx-cpd.com
    Keymaster

    Replying to Liz Bode 23/06/2024 - 20:52

    Hi Liz,

    No matter how many ECGs I look at, I still find them tricky! I’m looking forward to learning more from you and hopefully gaining some confidence in interpreting them.

    Best regards,

    Scott 🙂

    scott@vtx-cpd.com
    Keymaster

    Replying to Laura Jones 23/06/2024 - 11:26

    Hi Laura,

    Great to see you here! Thank you for being one of the speakers on this course. I’m really looking forward to your session.

    Thanks again for sharing your expertise with us!

    Best regards,

    Scott 🙂

    scott@vtx-cpd.com
    Keymaster

    Replying to Harry S. 22/06/2024 - 21:33

    Hi Harry,

    Great to see you here! Thank you for working with us and sharing your expertise. Your enthusiasm for fluid therapy is contagious! I’m looking forward to learning from your insights.

    Best regards,

    Scott 🙂

    scott@vtx-cpd.com
    Keymaster

    Really interesting Liz.

    Thanks for sharing!

    Scott 🙂

    scott@vtx-cpd.com
    Keymaster

    Hi Rosanna,

    For small animal internal medicine, I highly recommend “Ettinger’s Textbook of Veterinary Internal Medicine.” It’s widely considered the go-to resource in the field. There is a new edition available, which is quite comprehensive and detailed. It’s a two-volume text, so it is heavy-duty, but it also includes online access, which is a great bonus.

    You can find the latest edition here: https://www.evolve.elsevier.com/cs/product/9780323779319?role=student

    This textbook is often referred to as the “Internal Medicine Bible,” and it’s definitely the one I would go for if you’re looking for the most up-to-date and thorough resource. However, if you’re looking for something a bit more quick-fire and practical, I can make other recommendations. It would also be interesting to hear other people’s thoughts on this.

    This is definitely the most comprehensive text, with the benefit of being quite an up-to-date version. As you know, textbooks can become outdated quickly, so having the latest edition is crucial.

    Best regards,

    Scott 🙂

    scott@vtx-cpd.com
    Keymaster

    Replying to Aileen D. 19/06/2024 - 12:02

    Hello Aileen!

    Lovely to hear from you! I hope you are well! I will ask Felipe to answer this one!

    I hope you are enjoying the course.

    Scott 🙂

    scott@vtx-cpd.com
    Keymaster

    Replying to Felipe M. 14/06/2024 - 15:44

    Hi Felipe,

    Thanks for your insightful contribution! You make excellent points about the challenges and practicalities of using blood products in veterinary practice, particularly regarding availability and cost.

    I appreciate you highlighting the use of synthetic colloids as a temporary measure when blood products are not immediately accessible. It’s a pragmatic approach, especially in resource-limited situations.

    The reference to the CellSaver device is intriguing as well. It would indeed be a game-changer, albeit with the mentioned cost and caseload considerations.

    Great discussion all around!

    Best,
    Scott

    scott@vtx-cpd.com
    Keymaster

    Replying to Jon H. 14/06/2024 - 09:22

    Hi Jon,

    Thanks for your input! You make a good point regarding the availability and cost of blood products. It’s definitely a significant factor to consider in practice.

    I appreciate you sharing the paper on acute haemorrhage volume resuscitation. It’s always great to have more resources to better understand the implications of high-volume crystalloid resuscitation.

    Cheers,

    Scott

    scott@vtx-cpd.com
    Keymaster

    Replying to Neus E. 13/06/2024 - 18:20

    Thank you so much, Neus, for your insightful input and detailed explanation! Your expertise is greatly appreciated, and you’ve provided valuable information on managing haemorrhagic shock in these patients. Thanks again for taking the time to share your knowledge with us!

    Best regards,

    Scott

    scott@vtx-cpd.com
    Keymaster

    Just as a bit of a fun fact!

    Adobe-Stock-427094049

    The enrofloxacin issue is not thought to be as much of a problem in lions and tigers!

    Scott 🙂

    INVESTIGATION OF ENROFLOXACIN-ASSOCIATED RETINAL TOXICITY IN NONDOMESTIC FELIDS

    Kim M Newkirk, L Kathryn Beard, Xiaocun Sun, Edward C Ramsay

    Abstract
    Enrofloxacin is known to cause retinal toxicity in domestic cats. The hallmark lesion of enrofloxacin-associated retinal toxicity in domestic cats is thinning of the outer nuclear layer of the retina. Enrofloxacin is commonly used to treat bacterial infections in nondomestic felids because of its action against a wide spectrum of bacteria and the ability for it to be given orally. No previous studies have investigated the potential retinal toxicity of enrofloxacin in nondomestic felids. This retrospective study evaluated 81 eyes from 14 lions ( Panthera leo ) and 33 tigers ( Panthera tigris ) that had been enucleated or collected postmortem. The thickness of the outer nuclear retina was assessed in two separate sites in each eye by counting the rows of nuclei and by using digital image analysis software to determine the area of the nuclei at each site. Medical records were reviewed to determine the enrofloxacin dose for each cat. Cats that had not received enrofloxacin (n = 11) were compared with treated animals (n = 36). The outer nuclear layer thickness or area in treated versus untreated cats was not significantly different. Additionally, no clinical blindness was reported in any of the cats. This study showed no evidence of enrofloxacin-associated thinning of the outer nuclear layer in the lions and tigers evaluated, suggesting that enrofloxacin can be used safely in these animals.

    scott@vtx-cpd.com
    Keymaster

    Hello again.

    Here are some thoughts on this topic from one of our ECC specialists Neus:

    “So… yes I would use them in dogs with severe haemorrhagic diarrhoea/gastroenteritis a lot. I think I may be biased to the ones we see, so I am talking about the ones that come unwell with signs of hypovolaemic shock and severe dehydration/haemoconcentration. These ones typically come with high PCV and “normal” TS so for example 65%/60g/L, in these ones I know that if hypovolaemic I will need to fluid resuscitate so may end up needing 5-20mL/kg over a few boluses and then I will need high rates of IVFT to account for on going losses, rehydration and maintenance and when you calculate this sometimes is as high as 6-8mL/kg/h. There is two sides to this and one is that we know that actually the use of crystalloids itself will damage the glycocalyx and you will gave shedding and then this will lead to increased vascular permeability etc. and the second side to this is that when my PCV is normalised when the patient is rehydrated, say comes from 65 to 45%, I know my solids will ave tanked and probably be from 60 to 30-40g/L and at this stage this becomes a problem also with on going increased permeability, increased oncotic pressure etc. So that is why I tend to come in early with plasma to prevent this from happening, and when plasma is used as is a colloid… you can also allow yourself to use lower fluid rates so in the same example if you calculated you may need 6-8mL/kg/h if you combine plasma and crystalloids you may get away with 4-5mL/kg/h instead.

    For the hypoalbuminaemic GI patients… I don’t think there is a number really. So if I think PLE that I have treated alongside medicine; these patients are different as stable so unless I had to fluid resuscitate or need IVFT I would not consider it, even if their albumin is really low. Now for a PLE patient who isn’t great and is now third spacing and say it has abdominal effusion, and that is increasing the abdominal pressure which is compromising the gut blood supply and they are not doing great. I tend to remove abdominal fluid really slowly over a few hours, then replace with plasma – and the times we have done this they tend to have really low alb on low teens.”

    I hope that helps!

    Scott 🙂

    scott@vtx-cpd.com
    Keymaster

    Hi Rosie,

    I hope you are well! I wanted to share some insights from a recent conversation about the use of plasma transfusions in septic patients, focusing on the potential benefits of plasma in repairing the glycocalyx.

    Key Points:

    1. Fluid Therapy and Crystalloid Sparing:
    Neus highlighted that plasma can be used as a fluid therapy to provide oncotic support and reduce the volume of crystalloids needed. In septic patients, especially those with significant fluid losses and hypoproteinemia, plasma helps maintain colloid osmotic pressure (COP) and minimizes the damage to the glycocalyx caused by crystalloids.

    2. Glycocalyx Protection:
    The glycocalyx, a crucial component of the vascular endothelium, plays a significant role in vascular permeability and endothelial function. It can be damaged in conditions like sepsis, trauma, and inflammation. Animal studies suggest that resuscitation with plasma can partially restore the glycocalyx, whereas crystalloids and synthetic colloids do not have the same effect. This is potentially due to the albumin in plasma, which helps preserve endothelial integrity and reduce glycocalyx shedding.

    Practical Applications:

    HGE Cases:
    Neus also mentioned using plasma in dogs with severe hemorrhagic gastroenteritis (HGE), particularly those presenting with hypovolemic shock and severe dehydration. By combining plasma with crystalloids, we can use lower fluid rates and provide better oncotic support.

    Hypoalbuminemic Patients:
    For GI patients with severe hypoalbuminemia, Neus tends to use plasma when there’s third spacing or abdominal effusion. This helps stabilize albumin levels and supports vascular integrity.

    Questions and Considerations:

    Combining Plasma with Crystalloids:

    In septic patients, combining plasma with crystalloids can be beneficial. For instance, using plasma early on in resuscitation can help maintain COP and reduce the need for high crystalloid volumes.
    Using Plasma in Other Types of Shock:

    Plasma can be considered in other types of shock, such as hypovolemic shock in patients with protein-losing enteropathy (PLE), especially when albumin levels are critically low.
    Alternatives to Plasma:

    If plasma is not available, synthetic colloids could be considered for patients with low albumin, although they do not offer the same glycocalyx protection as plasma.
    Overall, the conversation emphasized the importance of considering plasma for its unique benefits, especially in maintaining the glycocalyx and providing oncotic support in critical patients.

    I will share some more specifics on HGE too!

    Best,

    Scott 🙂

Viewing 15 posts - 676 through 690 (of 2,377 total)