scott@vtx-cpd.com
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Replying to Neus E. 16/02/2024 - 22:12
Really helpful Neus!
It is even better when you can reference yourself! 🙂
I do not routenly in practice, but it is reassuring to hear your experience. I have popped the abstract to you papaer below.
Thanks again.
Scott 🙂
Indications for use and complications associated with canine plasma products in 170 patients
Abstract
Objectives: To describe a population of dogs receiving canine plasma products (PP), report the incidence of transfusion reactions (TR), and to identify whether this is higher when non-type-matched plasma is administered.
Design: Retrospective study conducted on dogs receiving canine PP between March 2016 and January 2018.
Setting: Private referral hospital with first opinion emergency clinic.
Animals: One hundred and ninety-four privately owned dogs identified from the clinic electronic medical record system that received at least 1 unit of canine PP during the study period; 25 patients were excluded due to incomplete records.
Interventions: None.
Measurements and main results: A search of computerized records was performed, identifying any patients that received canine PP between 2016 and 2018; clinical notes were examined to identify the number and type of TR associated. One hundred and sixty-nine cases were included in the study, receiving a total of 412 PP transfusions. Reactions were noted in 4% (17/412) of transfusions administered, with the vast majority being mild in nature. Of the TR identified, a greater proportion were in type-matched PP transfusions than non-type-matched, although this difference was not statistically significant (P = 0.7989). The number of dogs suffering a TR was higher (13%) when multiple units of plasma were administered than if only 1 unit was transfused (5%), but this was not statistically significant (P = 0.1161). Transfusion reactions were more likely to occur when packed red blood cells were also administered, although this was also not statistically significant (P = 0.07).
Conclusion: Administration of canine plasma products appears to be a safe procedure that carries a low risk of transfusion reactions. Type-matching of canine PP appears unnecessary and does not reduce incidence of TR in dogs.
Replying to Junwei Föhr 22/02/2024 - 22:24
Hello.
This could be a form of reverse sneezing, although it is not a totally ‘classic’ noise. It certainly sounds like it is coming from the naso-pharynx or the nasal cavity. The dog does seem to be gulping and salivating too. I would be worried this may have been triggered by a reflux event that has irritated the back of the throat.
Much of the investigation that I would recommend would depend on the persistence of the clinical signs. If the problem has subsided, I would not worry too much.
Hope that helps.
Scott 🙂
Replying to Jennifer Cartwright 20/02/2024 - 15:33
This is such a brilliant point Jenny!
I was looking at some references in the papers you mentioned, and the change in PCV can be quite significant. Definitely enough to make us consider different investigations for the patient. I have popped this other abstract below.
Thanks again for sharing!
Scott 🙂
Effects of a standardized anesthetic protocol on hematologic variables in healthy cats (JFMS)
Marc P Dhumeaux 1, Elisabeth C R Snead, Tasha Y Epp, Susan M Taylor, Anthony P Carr, Ryan M Dickinson, Marina L Leis
Abstract
This study evaluated the effects of an anesthetic protocol using intravenous ketamine and midazolam, and intramuscular buprenorphine on hematologic variables in cats. Twelve healthy adult cats had blood collected for a complete blood count before and after the induction of anesthesia. There were significant decreases in red blood cell counts, hemoglobin concentrations and hematocrits after the induction of anesthesia. On average, red blood cell counts and hematocrits decreased by 25%, and hemoglobin concentrations decreased by 24%. Based on hematocrit, 3/12 samples (25%) taken while the cats were anesthetized would have been interpreted as belonging to anemic patients while none of the cats would have been considered anemic before anesthesia. This study suggests that a complete blood count performed on blood taken under anesthesia with this anesthetic protocol should be interpreted cautiously in order to not make a false diagnosis of anemia.Replying to Michel O. 22/02/2024 - 22:40
Very cool!
I really love the academic environment, it is a great mix of clinical work, teaching and some research.
Thank you again for joining us on the course.
Scott 🙂
Replying to Emylia E. 22/02/2024 - 22:30
Hello Emylia!
I hope you are well and enjoying the course so far! I will make sure Felipe sees your brilliant question. I look forward to hearing his thoughts.
Scott 🙂
Replying to Rachel L. 23/02/2024 - 13:50
Hey Rachel.
I agree, it is always something that has felt like a good idea, but it is nice to have something to support it!
Really interesting comments regarding the cat with polycythaemia! What was the reason for the polycythaemia? Cat can be tricky to regularly draw larger volumes from, so this is a great shout and something I will consider in future. We had a couple of cases that we managed with medical leeches when I was a resident, but not done this in a while. Pretty cool though! I have popped a case report below:
Leeching as initial treatment in a cat with polycythaemia Vera
C. S. Net, P. Arnoldq, T. M. Glaus
Abstract
Polycythaemia Vera was diagnosed in a three-year-old domestic shorthaired cat referred because of seizures and a high packed cell volume (PCV). Laboratory examination revealed severe erythrocytosis (PCV 79 per cent). Diagnosis was reached by excluding causes for relative and secondary absolute polycythaemia. As phlebotomy proved impossible for initial treatment due to hyperviscosity, four leeches were used to suck blood and the PCV was consequently reduced to 64 per cent. A further 24 hours later, when bleeding at the sites of sucking had stopped, the PCV was 56 per cent. Long-term management of the condition was achieved with hydroxyurea (100 mg/cat once daily) and intermittent phlebotomy. Initial treatment using leeches in cases of polycythaemia Vera is a simple, non-invasive, well tolerated and effective method where phlebotomy is not possible.
Replying to Jennifer Cartwright 20/02/2024 - 15:48
This is so interesting Jenny, thank you so much for sharing.
Can I ask how you are currently assessing copper quantity/significance in tissue samples?
The opinion seems to vary a bit on how we should be doing it. Some people are happy on a histological score based on copper staining in tissue and others still measure DM copper in tissue?
What are your thoughts?
Scott 🙂
Replying to Junwei Föhr 20/02/2024 - 18:10
Hello Junwei,
I hope you are well. Thank you so much for sharing the video. Can you tell us a wee bit more about the dog? What is the signalment? Is the noise in the video the reason for presentation? Any other clinical signs.
I will look forward to seeing Jenny’s comments. I am happy to share some thoughts too.
Scott 🙂
Replying to Michel O. 19/02/2024 - 21:41
Michel!
How exciting that you are joining us! Are you working in small animal practice? I know on of the specialists at the vet school very well there, she has been trying to get me over to do some teaching… I might have to come visit.
I really hope you find the course useful. Please let us know if you have any questions.
Scott 🙂
Replying to Rachel L. 19/02/2024 - 19:22
Welcome Rachel!
Really lovely to have you here with us. Please make full use of the discussion forum and ask about any tricky cases that you are faced with in practice!
We are often very spoiled with anaesthesia in referral practice. I worded with Felipe for a number of years and did not really every have to think about the anaesthesia side of things. I am starting a new job next week and we do not have an anaesthesia specialist there… I am panicking already!
Hope you are having a lovely week!
Scott 🙂
Replying to Neus E. 16/02/2024 - 22:15
Hey.
Hope you are well. UA was looked at on a few occasions. The urine was persistently positive for bilirubin (4+), but also intermittently contained large amounts of free haemoglobin (4+, negative sediment).
Hope that helps.
Scott 🙂
Replying to Neus E. 16/02/2024 - 22:16
Welcome Neus!
Thank you again for your contribution. We are very lucky to be working with you!
Scott 🙂
Replying to Alys J. 12/02/2024 - 17:21
Hello Alys.
I hope you are well and enjoying the course. You can click at the top left of the lesson video to get the PDF notes. I have popped an image to help below:
Let me know if you have any problems.
Scott
Replying to Victoria Hughes 12/02/2024 - 06:29
Hey Victoria.
Thanks for the reply. I think it is an interesting discussion indeed.
I think the take home would be to avoid all other medications if possible!
I know that is easier said than done!
Scott 🙂
Replying to Victoria Hughes 12/02/2024 - 06:29
Hey Victoria.
Thanks for the reply. I think it is an interesting discussion indeed.
I think the take home would be to avoid all other medications if possible!
I know that is easier said than done!
Scott 🙂
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