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scott@vtx-cpd.com

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  • scott@vtx-cpd.com
    Keymaster
    13:11 20/06/22

    Hello Austeja.

    Thank you for sharing this really interesting case… and very frustrating! Thank you to Roz for her really helpful comments.

    I am not sure that the dietary diet is at play here. It would be unusual not to see an earlier increase in ALT. It would be great to get copper quantification on a liver sample (depending on what happens to the other dog).

    Leptospirosis testing can be tricky. I would definitely consider PCR blood and urine in acute cases. We can see false negatives with the PCR though, especially if the patient has been given previous antibiotics. I would also consider running serology. This will help confirm, especially paired serology 2-3 weeks apart showing rising titre.

    There definitely a risk of pathogen transmission through the raw feeding:

    https://pubmed.ncbi.nlm.nih.gov/35146110/

    Would be great to consider culture of fresh tissue if possible.

    Hope that helps.

    Scott 🙂

    scott@vtx-cpd.com
    Keymaster
    13:11 20/06/22

    Hello Austeja.

    Thank you for sharing this really interesting case… and very frustrating! Thank you to Roz for her really helpful comments.

    I am not sure that the dietary diet is at play here. It would be unusual not to see an earlier increase in ALT. It would be great to get copper quantification on a liver sample (depending on what happens to the other dog).

    Leptospirosis testing can be tricky. I would definitely consider PCR blood and urine in acute cases. We can see false negatives with the PCR though, especially if the patient has been given previous antibiotics. I would also consider running serology. This will help confirm, especially paired serology 2-3 weeks apart showing rising titre.

    There definitely a risk of pathogen transmission through the raw feeding:

    https://pubmed.ncbi.nlm.nih.gov/35146110/

    Would be great to consider culture of fresh tissue if possible.

    Hope that helps.

    Scott 🙂

    scott@vtx-cpd.com
    Keymaster
    11:57 20/06/22

    Replying to Hetty H. 17/06/2022 - 08:59

    Hello.

    I hope you are well. In many of the studies, it was only given for three days before. I think a week is totally sufficient in these cases. I normally do 3 days.

    I use TXA in most cases of bleeding problems, regardless of cause. It is probably helpful in cases of secondary coagulation problems and even thrombocytopenic patients.

    Hope that helps.

    Scott 🙂

    scott@vtx-cpd.com
    Keymaster
    10:59 20/06/22

    Replying to Idris Vandekinderen 19/06/2022 - 21:32

    Welcome Idris!

    I really hope you enjoy the course!

    Scott 🙂

    scott@vtx-cpd.com
    Keymaster
    17:50 15/06/22

    Replying to Joanne Maxwell 15/06/2022 - 13:31

    Hello Joanne.

    Thank you so much for joining the course, I really hope you enjoy the webinars.

    Let us know if you have any questions at any time.

    Scott 🙂

    scott@vtx-cpd.com
    Keymaster
    13:39 14/06/22

    Replying to Kaloyan K. 13/06/2022 - 20:26

    Hello.

    I hope you are well.

    Reported side effects include diarrhoea, vomiting, increased drinking and urination, drooling, nausea, abdominal pain, increased gastrointestinal sounds, head shaking, and lethargy. Bloodwork side effects include an increase in blood urea nitrogen and an increase in phosphorus levels.

    These are all more short term. From my own experience, I have not seen many of these side effects with short term use.

    There is a study looking at longer-term use, which suggests it is pretty safe too:

    https://pubmed.ncbi.nlm.nih.gov/27665742/

    Scott 🙂

    scott@vtx-cpd.com
    Keymaster
    13:33 14/06/22

    Replying to Grigory Brodetsky 13/06/2022 - 20:28

    Thanks again!

    Good to know Google is on our side!

    Have a great week.

    Scott 🙂

    scott@vtx-cpd.com
    Keymaster
    13:32 14/06/22

    Replying to Kaloyan K. 13/06/2022 - 20:34

    Interesting!

    How often are you using NAC in your liver cases?

    Scott 🙂

    scott@vtx-cpd.com
    Keymaster
    12:09 14/06/22

    Hello.

    I am so glad you enjoyed. There are a few protocols out there, but I would go with:

    IM regular insulin, not administered until patients have been adequately rehydrated with a stable cardiovascular system, is given at dosages of 0.2 U/kg initially and then 0.1 U/kg IM hourly until the blood glucose drops below 14 mmol/l, when insulin is given SC every 6 to 8 hours at dosages of 0.5 to 1 U/kg. Dextrose should be supplemented in the patient’s fluids as needed based on the patient’s blood glucose level.

    Hope that helps!

    Scott 🙂

    scott@vtx-cpd.com
    Keymaster
    19:35 13/06/22

    Replying to Grigory Brodetsky 12/06/2022 - 21:59

    Hello Grigory.

    Thank you for joining us from Canada!

    I really hope you enjoy the course.

    Scott 🙂

    scott@vtx-cpd.com
    Keymaster
    19:33 13/06/22

    Replying to Sarah Fiddy 11/06/2022 - 09:32

    Hello!

    Thank you for joining the course. We seem to have a strong Welsh contingent which is great to see!

    I hope you are having a great week.

    Scott 🙂

    scott@vtx-cpd.com
    Keymaster
    19:31 13/06/22

    Replying to Stefania Albrizio 10/06/2022 - 18:33

    Hello Stefania.

    Welcome to the course. Please let us know if you have any questions at anytime.

    Scott 🙂

    scott@vtx-cpd.com
    Keymaster
    18:53 09/06/22

    Replying to Hannah B. 09/06/2022 - 11:49

    Hello.

    Thank you so much for these kind words. I really hope you enjoyed the course. The JC recording is here:

    Gastrointestinal Journal Club Session 18.05.2022

    The Q&A should be uploaded under the lesson.

    Let me know if any problems.

    Scott 🙂

    scott@vtx-cpd.com
    Keymaster
    19:21 08/06/22

    Replying to Laura H. 08/06/2022 - 18:15

    Hello Laura.

    We are so pleased to have you on the course! I have an added level of respect that you are joining us from maternity leave!

    We actively encourage kids joining the live Q&A session! 🙂

    Hope you are having a great week.

    Scott 🙂

    scott@vtx-cpd.com
    Keymaster
    19:26 06/06/22

    Replying to Emma Holt 06/06/2022 - 18:04

    Emma!

    Fancy seeing you here! 🙂

    Thanks so much for your support and for joining the course.

    Scott 🙂

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