scott@vtx-cpd.com
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Replying to Nadia C. 24/06/2023 - 16:14
Another great question Nadia!
Bleeding due to amyloidosis is mostly a problem in cats. It can be a reason that cats would present with abdominal bleeding. The amyloid will deposit abnormally in the liver. This is an insoluble protein and will cause a change in the liver architecture. This makes the tissue more friable and prone to splitting/fracture. This is what makes the tissue more prone to bleeding.
I hope that makes sense!
Scott 🙂
Replying to Nadia C. 24/06/2023 - 16:12
Hello Nadia.
Another great question! The faecal occult blood test is generally detecting haemoglobin in the sample. That is the reason for the vegetarian diet. There are a few ways of running this test, so the methodology will have some effect on false positive/false negative results. I would try to stick to the vegetarian rule if possible. A great commercial option if Purina HA:
https://pubmed.ncbi.nlm.nih.gov/32196727/
I hope that helps.
Scott 🙂
Replying to Carolyn C. 28/06/2023 - 06:00
Hey Carolyn!
Really great question. So the answer does depend a little on the type of test being carried out, but generally better to do vegetarian if possible. This will probably not be too problematic for a few days in cats, but I understand your concern.
This study is helpful:
https://pubmed.ncbi.nlm.nih.gov/31509050/
In real life I would probably stick to Purina HA if possible (wet or dry based on this study) before doing FOB testing. I hope that helps.
Scott 🙂
Hello Nadia.
Really lovely to hear from you. I really hope you are enjoying the course.
Practically speaking I would use PT and aPTT to assess secondary coagulation in practice. These would be the methods that are most widely available.
There are different analysers that perform viscoelastic testing, including the ROTEM®, TEG® and Sonoclot®, results of which are not directly comparable (McMichael et al 2014). Even the same type of analyser does not yield comparable results in different institutions when subjected to standardized testing (Goggs et al 2018). To add confusion, each company uses specific terminology for the technique and results, which is only applicable to their analyser, although the provided results provide similar information. With the ROTEM® , the technique is called thrombelastrometry and with the TEG® analysers, the technique is called thrombelastography (abbreviated to TEG; the latter should only be used for results obtained from TEG® analysers and not those from the ROTEM® or Sonoclot®).
Generally speaking we have most information in veterinary medicine regarding TEG®. If there was the option to use thromboelastography then I would use that! The problem is that machines that perform this sort of testing are not widely used in practice (although commercially available). In time I am sure TEG will become more widely available.
What are you currently using?
Scott 🙂
Replying to Francesca Lamb 06/07/2023 - 09:24
Hey Fran!
I hope you are well and enjoying the course! I totally get it, it does seem like a bit of a scary procedure. It really is something that you should not have to resort to on many occasions. The blind BAL will suffice in most cases. This is really reserved for the super sick cases that you are worried about the GA in. I will try and look for more resources and chat through the procedure more at the live Q&A to get you feeling a bit more confident about it!
Scott 🙂
Replying to Nadia C. 27/06/2023 - 23:56
Hello Nadia.
I hope you are safe and well. No problem regarding journal club!
We can make the recording available if you would be keen to watch it back?
I really hope you are enjoying the course.
Scott 🙂
Replying to Kathryn B. 03/07/2023 - 16:04
Hey.
I have probably confused things a little by sharing the later blood results from day 23! The one thing we can be confident of is that the blood glucose was persistently high. The dog was diabetic… feel like that is not too much of a give away! 🙂
The main intervention between the 2 time points was insulin therapy was started.
There were some more investigations along the way too…
Scott 🙂
Replying to Kerry Doolin 25/06/2023 - 05:08
Well hello Kerry!
Amazing to have you join us. You obviously have to share a picture of the Pug now. These wee dogs have a funny way of making it into our lives! I don’t know if you remember we rescued one a wee while back too!
Scott 🙂
Replying to Talia C. 27/06/2023 - 19:07
Talia!
Brilliant to see you. You have had quite the career! How cool to have worked in so many incredible places.
I hope you enjoy the course and we can help a bit with the tricky anaemia cases.
Thank you again for supporting vtx.
Scott 🙂
Replying to Helen S. 19/06/2023 - 21:58
Thank Helen.
Honestly, I loved this!
I would live to hear peoples thoughts on this one!
I hope you are all having a lovely week.
Scott 🙂
Replying to Carolyn C. 20/06/2023 - 04:49
Carolyn!!!
Lovely to hear from you and thank you for joining us all the way from Sydney!
We are having lots of sunshine at the moment, but I am sure it is not at the level you are used to!
I hope you enjoy the course. Please let me know if you have any questions at any time.
Scott 🙂
Replying to Lindsay R. 14/06/2023 - 22:20
Hello Lindsay.
Sorry abaout that! I will ask Andy to look at this now!
I hope you are enjoying the course.
Scott 🙂
Replying to Nadia C. 14/06/2023 - 23:11
Hello Nadia!
Lovely to have you here. Thank you so much for learning with us.
I really hope you enjoy the course! I am really looking forward to the coagulation too!
Thanks again.
Scott 🙂
Replying to Anya W. 15/06/2023 - 07:11
Sounds exciting!
I am happy to help in amy way I can. I would obviously say that a medicine residency is the best option! 🙂
Scott
Replying to Francesca Lamb 11/06/2023 - 19:17
Hello again.
Yes, the recording will be avaiable to watch back.
Let me know if you have any questions you would like me to ask.
Scott 🙂
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