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Reply To: Phenobarbital toxicity

Homepage Forums Clinical Discussions Phenobarbital toxicity Reply To: Phenobarbital toxicity

Emma Holt

Hi Areti,

How did you get on with this case? Did the haematological abnormalities improve once the Phenobarb was stopped?

I came across my first case of phenobarb induced hepatoxocity a couple of weeks ago, (progressive elevation of ALT/ALP and dropping ALB, and acute onset PU/PD. Liver biopsies had histological changes which were consistent with phenobarb toxicity), so he is currently coming of his phenobarbitone and monitoring to see how his liver parameters respond.

I hope your patient is responding well.