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Reply To: Phenobarbital toxicity

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I honestly think I would be nervous too… but not sure there is a right or wrong answer here.

I suppose, depending on how badly controlled, you would need to give time for the potassium bromide to take effect.

Other drug considerations would be imepitoin or zonisamide. I would give the potassium bromide time in the first instance and maximise the dose of the levetiracetam in the short term to bridge the gap.

Interesting case. Let us know how things go!

Scott 🙂