Reply To: Ranitidine
This is a really interesting discussion.
In my gastroprotectants webinar, the main focus is regarding the use of ranitidine to modify the pH of the stomach and protect against reflux oesophagitis or help with the healing of gastroduodenal ulceration. Ranitidine is inferior to PPI’s like omeprazole for this purpose. It has been shown in in dog and cat studies to perform as well as placebo in modifying (increasing) gastric pH.
There is very little evidence in dogs to support the use of ranitidine as a prokinetic. One sketchy paper from the 80’s!
Having said all of that… rabbits are totally difference. I would be interested to see if anyone can shed any light on the literature surrounding this… definitely not my area!